Pregnancy
Scaling and root planning (SRP) with mouthwash use during pregnancy were associated with significantly lower risks of preterm birth (PTB) and low birth weight (LBW).
BMC Pregnancy and Childbirth
2024
Oral Health Status and Dental Services Utilization Among a Vulnerable Sample of Pregnant Women
The study sample showed relatively positive self-perceived oral health and dental visit patterns. However, the low rate of dental visits during pregnancy highlights the need for better integration of dental care into prenatal care.
International Dental Journal
2024
Pre-term (PT) children are at higher risk for developmental defects of enamel (DDE) in primary teeth and compromised periodontal health than full-term (FT) children. Children with extremely low birthweight (ELBW) are most susceptible for dental caries and gingivitis.
Dentistry Journal
2024
Using oral health care preventive services and visits to a dentist or dental clinic for problems during pregnancy was associated with decreased odds of having gestational diabetes and hypertensive disorders of pregnancy.
Journal of the American Dental Association (JADA)
2025
| Association between high birth weight and dental caries at 4-5 years of age: a birth-cohort study |
| High birth weight is a risk factor for early childhood caries. Particular attention should be paid to children with birth weight more than or equal to 4,000 g. |
| BMC Oral Health |
2024
| Stress and mental health symptoms in early pregnancy are associated with the oral microbiome |
| The oral microbiome is associated with stress and mental health in pregnant women, in ways different from the gut microbiome or what has been found in non-pregnant people. |
| BMJ Mental Health |
2024
| Association between periodontal disease and gestational diabetes: Systematic review and meta-analysis |
| Periodontal disease (PD) poses a high risk of suffering from gestational diabetes mellitus (GDM). The development of oral health programs in women who wish to conceive is essential to improve metabolic control and reduce obstetric and perinatal complications. |
| Primary Care Diabetes (PCDE) |
2024
Prevalence of periodontal disease in pregnancy: A systematic review and meta-analysis
It was observed a high prevalence of periodontal disease in pregnancy.
Journal of Dentistry
2022
Assessing the association between periodontitis and premature birth: a case-control study
The study results indicate that periodontitis is strongly associated with premature birth. Preventive solutions including the use of a periodontitis screening tool for nurses and midwives during antenatal care consultations, are highly recommended.
BMC Pregnancy and Childbirth
2021
Systematic review supports a low but existing association between perio and adverse pregnancy outcomes
National Library of Medicine
2016
In this article we describe the importance of the recognition, prevention, and treatment of oral health problems in pregnant women.
Journal of Obstetric, Gynecologic, & Neonatal Nursing (JOGNN)
2016
Aims to assess epidemiological evidence for the impact of perio disease on adverse pregnancy outcomes and identify potential underlying mechanisms.
Journal of Clinical Periodontology
2013
Alzheimer’s Disease and dementia
Alzheimer’s Disease and Dementia
Denture use may help protect against cognitive decline in older adults with partial tooth loss. This study highlights the potential importance of prosthodontic rehabilitation in preserving cognitive health.
Aging Medicine
2024
Our results confirmed that periodontitis was associated with both intra- and internetwork functional connectivity (FC) changes even in normal cognition (NC). The present study indicates that periodontitis might be a potential risk factor for brain damage and provides a theoretical clue and a new treatment target for the early prevention of Alzheimer disease.
Journal of Periodontology
2024
Poor Oral Health May Contribute to the Risk of Dementia
- Poor Oral Health Raises the Risk of Being Diagnosed with Alzheimer’s Disease & Related Dementias (ADRD)
- ADRD Negatively Affects Oral Health and Requires Additional Care
- Questions Remain about the Relationship Between ADRD and Oral Health
- Research Can Help Fill in the Knowledge Gaps
CareQuest Institute for Oral Health
2024
Patients with periodontal disease are significantly more likely to develop Alzheimer’s disease than those who are periodontally healthy. This interaction is thought to be mediated by inflammation, the periodontal microbiome, and the immune reactions to those pathogens that are associated with the oral biofilm.
Dental Academy of Continuing Education
2023
Diabetes, Edentulism, and Cognitive Decline: A 12-Year Prospective Analysis
Our study finds the co-occurrence of Diabetes mellitus (DM) and edentulism led to a worse cognitive function and a faster cognitive decline in older adults aged 65 to 74.
Sage Journals
2023
Poor periodontal health and tooth loss appear to increase the risk of both cognitive decline and dementia. However, the available evidence is limited to draw firm conclusions.
Journal of the American Geriatrics Society
2022
This review suggests that periodontal infection is associated with Alzheimer’s Disease. The contributing microbiome remains unconfirmed, possibly because of different microbiome sampling sites or methods.
Journal of Dental Sciences
2022
The findings provide a theoretical basis for the study of the relationship between F. nucleatum and AD and lay a preliminary foundation for further exploring the mechanism of F. nucleatum impact on the onset and development of Alzheimer’s Disease
Frontiers
2022
Dose-Response Meta-Analysis on Tooth Loss With the Risk of Cognitive Impairment and Dementia
Moderate-quality evidence suggested tooth loss was independently associated with cognitive impairment and dementia; risk of diminished cognitive function increased with incremental numbers of teeth lost. Further, timely prosthodontic treatment with dentures may reduce the progression of cognitive decline related to tooth loss.
Journal of Post-Acute and Long-Term Care Medicine
2021
Obstructive sleep apnea treatment and dementia risk in older adults
PAP treatment and adherence are independently associated with lower odds of incident AD diagnoses in older adults. Results suggest that treatment of OSA may reduce the risk of subsequent dementia.
Sleep
2021
The results of the present study using Japanese dental claims data showed that older people visiting dental offices with fewer teeth present and a greater number of missing teeth are more likely to have Alzheimer’s disease.
PLOS One
2021
Periodontal dysbiosis associates with reduced CSF Aβ42 in cognitively normal elderly
To our knowledge, this is the first report of an association between subgingival periodontal bacteria and CSF biomarkers of AD pathology in cognitively normal elderly people. We found that subgingival periodontal dysbiosis characterized by increases in periodontal‐associated bacteria and decreases in health‐related bacteria associated with reduced CSF Aβ42 but not with CSF P‐tau.
Alzheimer’s Association
2021
Periodontal disease and incident dementia: The Atherosclerosis Risk in Communities Study (ARIC)
Supports a modest association between perio disease and incidence of mild cognitive impairment and dementia
Neurology – American Academy of Neurology
2020
This study provides evidence for an association between periodontal pathogens and AD, which was stronger for older adults.
Journal of Alzheimer’s Disease
2020
Evaluates the mechanisms underlying the potential link between perio disease and Alzheimer’s disease
Science Advances — American Assoc for the Advancement of Science
2019
Association between Periodontitis and Alzheimer’s Disease
Evaluates the potential link between perio disease and Alzheimer’s disease with goal of identifying novel mechanisms and interventional strategies to improve patient outcomes
NIH – US Library of Medicine
2015