Obesity
The causal relationship between the three exposures (alcohol consumption, BMI, and sleep duration) and mouth ulcers was analyzed, partially mediated by circulating cytokines, metabolites, and plasma proteomes.
Health Science Reports
2026
These findings reveal mechanistic oral microbiome-metabolite shifts, highlighting oral microbiome-host interactions as novel targets for obesity prevention and intervention.
Cell Reports
2026
Bariatric Surgery Alters Oral Microbiome: Evidence From Obese Patients and a Mouse Model
Bariatric surgery (BaS) exacerbates obesity-related microbial dysbiosis, increasing the risk of periodontal and dental diseases. Paradoxically, while BaS improves systemic and cardiometabolic health, it appears to worsen oral outcomes, underscoring the need for integrated medical–dental care and preventive protocols in this population.
International Dental Journal
2025
Obesity and orthodontic treatment: A scoping review
Orthodontists and dentists should incorporate BMI evaluation in the overall treatment diagnosis and educate patients about the negative impact of obesity on general and oral health.
Seminars in Orthodontics
2025
Relationship between three body obesity indicators, WWI, BMI, WtHR, and periodontitis
This cross-sectional study exposed a positive correlation between WWI (weight-adjusted-waist index), WtHR (waist-to-height ratio), and periodontitis and this positive correlation showed an age difference.
Scientific Reports
2025
Obesity is associated with a higher prevalence of gingival inflammation
Obesity was associated with a higher prevalence of gingival bleeding, while overweight status showed no significant association. These results suggest that obesity, rather than overweight, is associated with increased gingival inflammation.
Obesity Medicine
2024
Dentition and weight status in community-dwelling older adults
Older adults with tooth loss – especially loss of posterior occlusion and lack of a functional dentition – were more likely to be obese than of normal weight.
Gerodontology
2024
Adiposity is not associated with caries among youth in the United States
The authors found no association between measures of adiposity and caries among US children and adolescents.
JADA
2023
Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
- Obesity establishes an IFN-I-deprived tumor microenvironment and increases tumor burden
- Myeloid cells from obese hosts are desensitized to STING stimulation
- Saturated fatty acids inhibit the STING pathway by inducing NLRC3
- NLRC3 inhibits the immunogenicity of HNSCC in an IFN-I-dependent fashion
Cell Reports
2023
Comparing the relative influence of obesity and ancestry on timing of dental development
Body Mass index (BMI) appears to have a greater impact on relative timing of dental development than ancestry in this population. Our results support other findings that obesity results in accelerated growth and development.
Orthodontics and Craniofacial research
2023
Risk Factors for Dental Erosion After Bariatric Surgery: A Patient Survey
This long-term cross-sectional study suggests a time-dependent, increasing occurrence of vomiting and acidic reflux after bariatric surgery. Vomiting and reflux became even more common after 5 to 10 years. A significant relationship emerged between a high frequency of acidic reflux and a high frequency of oral symptoms related to dental erosion.
International Dental Journal
2022
We found that an increase in BMI was associated with a decrease in the number of residual teeth from younger ages independently of smoking status and diabetes in the large scale of Japanese database.
Plos One
2020