General
Our results suggest that Neutrophil percentage-to-albumin ratio (NPAR) is significantly linked to poor periodontal health. However, owing to the cross-section design of this study, additional longitudinal studies are necessary to further enhance our comprehension of the impact of NPAR on periodontal status.
International Dental Journal
2025
Our results suggest that Neutrophil percentage-to-albumin ratio (NPAR) is significantly linked to poor periodontal health. However, owing to the cross-section design of this study, additional longitudinal studies are necessary to further enhance our comprehension of the impact of NPAR on periodontal status.
International Dental Journal
2025
These findings demonstrate that approximately 75% of patients, independently from their socio-economic status, periodontal health status, frequency of dental visits and perceived access to care, still ignored the link between periodontitis and other diseases. The level of awareness was low even among patients suffering from periodontitis or from cardiovascular diseases, cancer and diabetes, which have been extensively associated with periodontitis
Periodontology
2024
The value-for money of preventing and managing periodontitis: Opportunities and challenges
This article gives an overview of the societal and economic aspects of periodontitis and periodontal care.
Periodontology
2024
Self-reported oral health is associated with systemic health outcomes and all-cause mortality
Self-reported oral health had a similar magnitude of associations with systemic comorbidities as established with periodontal disease previously. Moreover, self-rated fair or poor oral health, suboptimal dental visits, or infrequent flossing were associated with increased all-cause mortality.
JADA
2024
Oral Health and Mortality Among Older Adults: A Doubly Robust Survival Analysis
This study aims to investigate the link between oral health and mortality in community-dwelling older adults by adjusting for confounding factors with a doubly robust survival estimation. Edentulism was associated with a reduction in survival time.
American Journal of Preventive Medicine
2022
Time-varying periodontal status assessed using radiographic alveolar bone loss (ABL) was positively associated with all-cause mortality even after confounder adjustment.
Journal of Clinical Periodontology
2022
Preventive dental care is strongly associated with significant savings for diabetes and CAD patients, and such savings were highest for diabetes + CAD patients, followed by patients with only CAD and only diabetes. Most of these savings originated in costs associated with inpatient admissions, which were between 25% and 36% for all disease classifications for all years.
Compendium of Continuing Education in Dentistry
2022
Article: Maintaining Oral Health Is Essential to Well-Being
Maintaining oral health is essential to general health and well-being. Oral conditions affect more than just the mouth and teeth. Poor oral health increases the risk of developing chronic conditions, such as cardiovascular disease and diabetes.
Pharmacy Times
2022
In this cohort, periodontal diseases appeared to be associated with an increased risk of developing cardiovascular, cardiometabolic, autoimmune diseases and mental ill health. Periodontal diseases are very common; therefore, an increased risk of other chronic diseases represent a substantial public health burden.
BMJ Journals
2021
Human variation in gingival inflammation
Article: Study reveals new aspects of gingivitis and the body’s response
Sheds important new light on why some people may be more prone to serious conditions that lead to tooth loss and other problems.
PNAS
2021
Dental Services and Health Outcomes in the New York State Medicaid Program
Observed that accessing preventive dental care by a large cohort of publicly insured individuals in New York State was associated with better health care outcomes, most notably for the rates and costs of inpatient admissions.
Journal of Dental Research
2021
Periodontal Inflammation Primes the Systemic Innate Immune Response
Provides clinical rationale for perio-systemic disease links
Journal of Dental Research
2020
Provides support of correlative; not causative perio-systemic links
CDC – Systematic Review (Volume 16)
2019
Back to top Periodontitis and Diabetes Complications: A Danish Population-Based Study
Diabetic neuropathy and retinopathy, individually and combined, were associated with moderate/severe periodontitis. In addition, dyslipidemia had an additive positive effect modification on diabetic microvascular complications, elevating the odds of moderate/severe periodontitis.
Sage Journals
2024
Periodontal Disease and Metabolic Syndrome in Women at Prior High Risk for Gestational Diabetes
Periodontal disease was associated with insulin resistance and metabolic syndrome (MetS) in women at prior high risk of developing gestational diabetes.
Clinical and Experimental Dental Research
2024
Diabetes prevalence was associated with higher dental caries experience.
Elsevier Public Health
2025
This study provides a significant contribution of periodontal disease (PD) to the increase in health care expenditure (HCE), particularly in individuals with diabetes mellitus (DM).
Journal of Periodontology
2025
Using oral health care preventive services and visits to a dentist or dental clinic for problems during pregnancy was associated with decreased odds of having gestational diabetes and hypertensive disorders of pregnancy.
Journal of the American Dental Association (JADA)
2025
| Regular periodontal disease prevention and management under professional care before type 2 diabetes mellitus onset contribute to improved health and reduced medical costs. |
| Primary Care Diabetes (PCDE) |
2024
| Periodontal disease (PD) poses a high risk of suffering from gestational diabetes mellitus (GDM). The development of oral health programs in women who wish to conceive is essential to improve metabolic control and reduce obstetric and perinatal complications. |
| Primary Care Diabetes (PCDE) |
2024
Insulin resistance and periodontitis: Mediation by blood pressure
The triglyceride-glucose (TyG) index was associated with increased odds of moderate / severe periodontitis, especially in individuals with obesity, hypertension, and dyslipidemia. Systolic blood pressure (SBP) levels partially mediated this association.
| Journal of Periodontal Research |
2024
Results suggest that gargling with mouthwash reduces the number of red complex species and improves the hyperglycemic status in patients with type 2 diabetes mellitus, especially younger patients.
Scientific Reports
2024
Treatment of periodontitis for glycaemic control in people with diabetes mellitus
We included 35 studies, which randomised 3249 participants to periodontal treatment or control.
Cochrane Library
2022
Type 1 diabetes mellitus negatively affects tooth enamel and dentine microhardness: An in-vivo study
T1DM negatively affected enamel and dentine microhardness, and enamel was influenced much more negatively and rapidly compared with dentine in diabetic groups.
Archives of Oral Biology
2022
Preventive dental care is strongly associated with significant savings for diabetes and CAD patients, and such savings were highest for diabetes + CAD patients, followed by patients with only CAD and only diabetes.
Compendium of Continuing Education in Dentistry
2022
Association between type 2 diabetes (T2D) and tooth loss: a systematic review and meta-analysis
The findings suggest that T2D is associated with increased risk of tooth loss.
BMC Endocrine Disorders
2022
Frequent tooth brushing was associated with reduced risks of incident hypertension and T2DM. Tooth brushing at least twice a day may prevent future hypertension and T2DM events.
Journal of Hypertension
2022
Findings suggest that improvement in oral health, including the maintenance of masticatory function and remaining teeth, may contribute to the prevention of sarcopenia and diabetes mellitus in older adults.
PLOS One
2021
The risk of tooth loss in patients with diabetes: a systematic review and meta-analysis
There is moderate certainty for a small but significantly higher risk of tooth loss in Diabetes patients as compared to those without Diabetes.
International Journal of Dental Hygiene
2021
Effect of Diabetes on Rotary Instrumentation of Dentin
Diabetes mellitus may affect the physical and mechanical properties of dentin, which could potentially have an impact on root canal procedures.
Journal of Endodontics
2021
Implementation of an oral care protocol in primary diabetes care improved oral health-related quality of life in patients with type 2 diabetes
Annals of Family Medicine
2021
Improved oral hygiene is associated with decreased risk of new-onset
Diabetes: a nationwide population-based cohort study
Provides evidence that oral hygiene reduces new onset T2D
Springer Verlag
2020
Provides evidence that diabetes increases perio risk
National Library of Medicine
2018
In this systematic review and meta-analysis, there is a significant reduction of Glycated hemoglobin and Fasting plasma glucose level on type 2 diabetic and periodontal patients with non-surgical periodontal therapy.
BMC Oral Health
2016
Supporting evidence that perio treatment improves T2D control
Journal of Clinical Periodontology
2013
Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence
Provides evidence to suggest that perio disease adversely affects diabetes outcomes
Journal of Clinical Periodontology
2013