Diabetes

Xerostomia and Salivary Dysfunction in Patients With Diabetes Mellitus. A Cross-Sectional Study

The possible association between Diabetes mellitus (DM), xerostomia, and/or hyposalivation is complex and may be influenced by multiple factors.

Journal of Oral Pathology and Medicine

2024

Dental caries and salivary alterations in patients with type 2 diabetes: A systematic review and meta-analysis

Type 2 diabetes may lead to an increased index of dental caries and a reduction in salivary flow rate, salivary pH, and salivary buffering capacity in adults.

Journal of Dentistry

2024

Periodontitis and Diabetes Complications: A Danish Population-Based Study

Diabetic neuropathy and retinopathy, individually and combined, were associated with moderate/severe periodontitis. In addition, dyslipidemia had an additive positive effect modification on diabetic microvascular complications, elevating the odds of moderate/severe periodontitis.

Sage Journals

2024

Periodontal Disease and Metabolic Syndrome in Women at Prior High Risk for Gestational Diabetes

Periodontal disease was associated with insulin resistance and metabolic syndrome (MetS) in women at prior high risk of developing gestational diabetes.

Clinical and Experimental Dental Research

2024

Assessing the relationship between diabetes mellitus and dental caries among US adults: The National Health and Nutrition Examination Survey (NHANES) 2013-20

Diabetes prevalence was associated with higher dental caries experience.

Elsevier Public Health

2025

Differences in health care expenditure due to the comorbidity status of periodontal disease and diabetes mellitus

This study provides a significant contribution of periodontal disease (PD) to the increase in health care expenditure (HCE), particularly in individuals with diabetes mellitus (DM).

Journal of Periodontology

2025

Use of oral health services among pregnant women and associations with gestational diabetes and hypertensive disorders of pregnancy

Using oral health care preventive services and visits to a dentist or dental clinic for problems during pregnancy was associated with decreased odds of having gestational diabetes and hypertensive disorders of pregnancy.

Journal of the American Dental Association (JADA)

2025

Analysis of the impact of periodontal disease management before the onset of type 2 diabetes mellitus on medical costs using administrative claims database

Regular periodontal disease prevention and management under professional care before type 2 diabetes mellitus onset contribute to improved health and reduced medical costs.
Primary Care Diabetes (PCDE)

 

2024

Association between periodontal disease and gestational diabetes: Systematic review and meta-analysis

Periodontal disease (PD) poses a high risk of suffering from gestational diabetes mellitus (GDM). The development of oral health programs in women who wish to conceive is essential to improve metabolic control and reduce obstetric and perinatal complications.
Primary Care Diabetes (PCDE)

 

2024

Insulin resistance and periodontitis: Mediation by blood pressure

The triglyceride-glucose (TyG) index was associated with increased odds of moderate / severe periodontitis, especially in individuals with obesity, hypertension, and dyslipidemia. Systolic blood pressure (SBP) levels partially mediated this association.

Journal of Periodontal Research

2024

Effects of mouthwash on periodontal pathogens and glycemic control in patients with type 2 diabetes mellitus

Results suggest that gargling with mouthwash reduces the number of red complex species and improves the hyperglycemic status in patients with type 2 diabetes mellitus, especially younger patients.

Scientific Reports

2024

Treatment of periodontitis for glycaemic control in people with diabetes mellitus

We included 35 studies, which randomised 3249 participants to periodontal treatment or control.

Cochrane Library

2022

Type 1 diabetes mellitus negatively affects tooth enamel and dentine microhardness: An in-vivo study

T1DM negatively affected enamel and dentine microhardness, and enamel was influenced much more negatively and rapidly compared with dentine in diabetic groups.

Archives of Oral Biology

2022

Association Between Preventive Dental Care and Healthcare Cost for Enrollees With Diabetes or Coronary Artery Disease: 5-Year Experience

Preventive dental care is strongly associated with significant savings for diabetes and CAD patients, and such savings were highest for diabetes + CAD patients, followed by patients with only CAD and only diabetes.

Compendium of Continuing Education in Dentistry

2022

Association between type 2 diabetes (T2D) and tooth loss: a systematic review and meta-analysis

The findings suggest that T2D is associated with increased risk of tooth loss.

BMC Endocrine Disorders

2022

Associations of oral hygiene with incident hypertension and type 2 diabetes mellitus: A population based cohort study in Southwest China

Frequent tooth brushing was associated with reduced risks of incident hypertension and T2DM. Tooth brushing at least twice a day may prevent future hypertension and T2DM events.

Journal of Hypertension

2022

Number of teeth and masticatory function are associated with sarcopenia and diabetes mellitus status among community-dwelling older adults: A Shimane CoHRE study

Findings suggest that improvement in oral health, including the maintenance of masticatory function and remaining teeth, may contribute to the prevention of sarcopenia and diabetes mellitus in older adults.

PLOS One

2021

The risk of tooth loss in patients with diabetes: a systematic review and meta-analysis

There is moderate certainty for a small but significantly higher risk of tooth loss in Diabetes patients as compared to those without Diabetes.

International Journal of Dental Hygiene

2021

Effect of Diabetes on Rotary Instrumentation of Dentin

Diabetes mellitus may affect the physical and mechanical properties of dentin, which could potentially have an impact on root canal procedures.

Journal of Endodontics

2021

Implementation of an Oral Care Protocol for Primary Diabetes Care: A Pilot Cluster-Randomized Controlled Trial

Implementation of an oral care protocol in primary diabetes care improved oral health-related quality of life in patients with type 2 diabetes

Annals of Family Medicine

2021

Improved oral hygiene is associated with decreased risk of new-onset

Diabetes: a nationwide population-based cohort study

 

Provides evidence that oral hygiene reduces new onset T2D

Springer Verlag

2020

Does diabetes increase the risk of periodontitis? A systematic review and meta-regression analysis of longitudinal prospective studies

Provides evidence that diabetes increases perio risk

National Library of Medicine

2018

The effect of periodontal therapy on glycemic control and fasting plasma glucose level in type 2 diabetic patients

In this systematic review and meta-analysis, there is a significant reduction of Glycated hemoglobin and Fasting plasma glucose level on type 2 diabetic and periodontal patients with non-surgical periodontal therapy.

BMC Oral Health

2016

Evidence that periodontal treatment improves diabetes outcomes: a systematic review and meta-analysis.

Supporting evidence that perio treatment improves T2D control

Journal of Clinical Periodontology

2013

Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence

Provides evidence to suggest that perio disease adversely affects diabetes outcomes

Journal of Clinical Periodontology

2013

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