Additional Connections

Liver function

The relationship between fixed dental prostheses, blood lead levels, and liver function: Mediating effects and gender differences

An increased count of fixed prostheses is associated with changes in liver function markers in a gender-dependent manner, with blood lead levels serving as a potential mediator in males.

Environmental Pollution

2024

Sleep

Dentofacial deformities as independent predictors of sleep disorders: a cross-sectional study of young adults

Findings suggest a significant association between dentofacial characteristics and sleep quality in young adults. Protruding facial profiles and anterior crossbites were identified as independent predictors for sleep disorders (SDs). These findings underscore the importance of screening for SDs in individuals with dentofacial deformities and highlight the potential benefits of early correction of such dentofacial abnormalities to reduce the risk of SDs in adulthood.

BMC Oral Health

2025

Gut Health

Oral microbiota shifts following tooth loss affect gut health

In the mouse model, tooth loss disrupted the balance of the oral-gut microbiota, with potential implications for intestinal health. Although these findings are from a murine model, considering the existence of the oral-gut axis balance in the human body, it is reasonable to postulate that following tooth loss in humans, the health of the intestinal microecology may also warrant attention.

BMC Oral Health

2025

Abscesses

Association of periodontal disease and the prevalence of acute periapical abscesses

Under the conditions of this study, it appears that the odds for acute periapical abscesses (PAs) are significantly higher in patients with periodontal disease (PD) seeking treatment for pain due to acute PAs.

Journal of the American Dental Association

2025

Epilepsy

Causal relationship between oral microbiota and epilepsy risk: Evidence from Mendelian randomization analysis in East Asians

This study underscores the effect of oral microbiota (OM) on epilepsy, suggesting potential mechanisms between the OM and epilepsy. Further investigation into the potential role of the OM is needed to enhance our in-depth understanding of the pathogenesis of epilepsy.

Epilepsia Open

2024

Bone density New insights into the correlation between bone mineral density and dental caries in NHANES 2011-2016
Monitoring bone mineral density (BMD) should be combined with appropriate oral healthcare and caries management strategies to effectively address these interconnected health issues, and particular attention should be paid to the monitoring of head BMD.
Scientific Reports

2024

ADHD

Attention deficit hyperactivity disorder and dental traumatic injuries: a systemic review and meta-analysis

The findings of this study suggest a significant association between attention deficit hyperactivity disorder (ADHD) and an increased risk of traumatic dental injuries (TDIs). Individuals with ADHD were found to be nearly 2x as likely to experience TDIs compared to those without ADHD.

European Review for Medical and Pharmacological Studies

2024

Alopecia

Periodontitis and risk of alopecia areata: A nationwide population-based cohort study in Korea

Patients with periodontitis may be at a much greater risk of developing alopecia areata, an autoimmune disease characterized by hair loss, according to a study published on November 17 in the Journal of the European Academy of Dermatology and Venereology.

Journal of the European Academy of Dermatology and Venereology

2022

Asthma

Association between asthma and periodontal disease: A systematic review and meta-analysis

Data from this systematic review strongly suggest the association of asthma with periodontal disease.

Journal of Periodontology

2018

Athletics

The impact of oral health on physical fitness: A systematic review

Oral health problems may have numerous effects on general health, including physical fitness and performance. In this review, we aimed to systematically review the available evidence to assess the effect of oral health on general physical fitness.

Heliyon

2020

Auto-immune

Burden of chronic diseases associated with periodontal diseases: a retrospective cohort study using UK primary care data

In this cohort, periodontal diseases appeared to be associated with an increased risk of developing cardiovascular, cardiometabolic, autoimmune diseases and mental ill health.

BMJ Open

2022

Bone marrow disease

Oral health status of patients with inherited bone marrow failure syndromes

Oral health may be impaired in these patients related to the disease itself, due to cytopenia, or related to the drugs the patients use, such as glucocorticoids.

Pediatric Dental Journal

2022

Celiac Disease

Celiac disease and its implications on the oral health of children: A systematic review

Oral manifestations may precede gastrointestinal symptoms. Patients presenting such manifestations should be screened for coeliac disease. The cooperation of gastroenterologists and dentists could lead to an increased detectability of coeliac disease.

Journal of Pediatrics and Child Health

2023

Oral and dental manifestations of celiac disease in children: a case-control study

(Saudi) children with Celiac Disease had a greater number of clinical findings of recurrent aphthous stomatitis (RAS) and dental enamel defects (DEDs) than healthy controls.

BMC

2022

COVID

Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study

In this retrospective explorative pilot study, alveolar bone loss and tooth loss are associated with the severity of COVID-19, however they are not independent risk factors.

Advances in Oral and Maxillofacial Surgery

2021

Erectile Dysfunction

Associations of remaining teeth number, periodontal disease, and occlusal support status with erectile dysfunction in community-dwelling men

Poor occlusal support status was significantly associated with Erectile Dysfunction (ED) in community-dwelling men, as opposed to remaining teeth number and periodontal health status.

International Journal of Urology

2024

Eye health

Association between poor oral health and risk of glaucoma

 

Article
Eye spy: Exploring the mouth-eye connection (EXCELLENT FOOTNOTES)

The purpose of our study was to explore further the association between chronic periodontitis and glaucoma in a retrospective case-control study design.

Investigative Ophthalmology and Visual Disease

2022

Hip Replacement

The Association of Dental Caries or Dental Implant Placement Within One Year of Primary Total Hip Arthroplasty on Medical and Implant Complications

Dental diagnoses within 12 months of Total hip arthroplasty (THA) are associated with increased medical complications. Dental diagnoses occurring 12 months after THA are associated with greater implant-related complications, including periprosthetic joint infections (PJIs). Delaying invasive dental procedures for 12 months after THA may be advisable.

The Journal of Athroplasty

2024

HIV

Postmenopausal women with HIV have increased tooth loss

Postmenopausal women with HIV have deterioration of the alveolar trabecular bone microarchitecture that may contribute to greater tooth loss.

BMC Oral Health

2024

Hemophilia

Assessment of Oral Health and Healthy Habits in Adult Patients with Congenital Hemophilia

Patients with hemophilia have an increased risk of developing dental caries.

European Journal of Dentistry

2022

Oral Microbiome

Oral microbiome and pancreatic cancer

Combined symptom and microbiome evaluation may help in the early detection of pancreatic cancer.

World J Gastroenterol.

2020

Pneumonia

Oral health status of patients with inherited bone marrow failure syndromes

Article:
Hospital-Acquired Pneumonia Is Killing Patients. Yet There Is a Simple Way to Stop It.

Lack of dental care during inpatient stays may be responsible for hundreds of thousands of hospital-acquired infections each year, including nonventilator hospital-acquired pneumonia, which can be fatal in up to 30% of infected patients, especially those lying flat or staying immobile for long periods of time. A greater focus on brushing patients’ teeth regularly during hospital stays is needed, some experts say.

Kaiser Health News

2022

Sleep

Sleep Duration and Risk of Periodontitis-A Systematic Review and Meta-Analysis

The present review indicated that too little sleep duration (≤5 hours) significantly increased the risk of periodontitis. However, the evidence is limited due to cross-sectional design of most studies, hence longitudinal studies should be conducted to support this finding.

International Dental Journal

2024

Sleep apnea

Is periodontitis associated with obstructive sleep apnea? A systematic review and meta-analysis

According to the results, periodontitis has been shown to be associated with mild-to-moderate obstructive sleep apnea (OSA), but not with severe OSA.

Journal of Clinical and Experimental Dentistry

2022

Sjogren’s Syndrome

Characterizing clinical findings of Sjögren’s Disease patients in community practices using matched electronic dental-health record data

 

This study of Sjogren’s Disease patients diagnosed in community practices characterized three different Sjogren’s Disease clinical presentations, which can be used to generate Sjogren’s Disease study cohorts for longitudinal studies using electronic health record data.

Plos One

2023

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