Pain Management
Full spectrum cannabidiol oil improved pain and quality of life with a favorable safety profile, supporting further investigation.
Oral Medicine Oral Medicine Oral Pathology Oral Radiology
2026
Exploring post-traumatic stress among patients at a clinic for orofacial pain and dysfunction
The presence of PTSD in this clinical sample was associated with the presence of painful TMD and awake bruxism. The presence of a reported potentially traumatic event without PTSD was not associated with painful TMD or awake bruxism. Finally, when examining symptom severity, the severity of awake bruxism was correlated to post-traumatic stress symptoms.
Journal of Dentistry
2025
Spinal pain in preadolescence was associated with significantly higher odds of painful temporomandibular disorders (p-TMD)and headache in young adulthood. These findings suggest that preadolescent spinal pain may represent an early marker of vulnerability to p-TMD and headache in young adulthood.
The Journal of Pain
2026
Low oral health scores correlated with higher pain scores. Both were associated with higher relative abundance of oral pathobionts. This suggests a potential role for the oral microbiota in the aetiology of pain experienced by women with migraine headache and abdominal and body pain. These findings prompt consideration of an oral microbiome–nervous system axis.
Frontiers in Pain Research
2025
The Ca2+ channel ORAI1 is a regulator of oral cancer growth and nociceptive pain
We report here that the function of the Ca2+ channel ORAI1 is an important regulator of oral cancer pain.
Science Signaling
2023
International Trends in Dental Opioid Prescriptions
This cross-sectional study found that the US dental opioid dispensing rate is decreasing but remains high by international standards. Findings suggest opportunities to reduce this rate exist. This notion is further supported by data showing that two-thirds of US dental opioid prescriptions are for tooth extraction, a procedure for which ibuprofen and acetaminophen are equally effective for pain control.4,5 Compared with the Netherlands, Germany, and Belgium, dental opioid dispensing rates were consistently higher in Canada, France, Australia, and Puerto Rico, suggesting opportunities to reduce these rates may also exist.
JAMA Network
2026
Effectiveness of curcumin mouthwash in preventing traumatic ulcers in orthodontic patients
Although ulcer prevention was not observed, curcumin mouthwash may serve as an adjunct for early pain relief in orthodontic patients.
BMC Oral Health
2025
Is there a link between diet and painful temporomandibular disorders? A cross-sectional study
Painful TMD is associated with higher psychosocial distress and poorer dietary quality. These findings underscore the need to include dietary assessment in the clinical evaluation and management of TMD.
BMC Oral Health
2025